Product & ReviewsAntibodies
TNF-alpha Antibody
Product Details
- Cat. No.
- 250844
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Tumor necrosis factor alpha (TNF-alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces cell death of certain tumor cell lines. It is a potent pyrogen causing fever by direct action or by stimulation of IL-1 secretion, and therefore found in cachexia accompanying diverse cancers and infections. Genetic variations in TNF are associated with susceptibility to psoriatic arthritis and to HBV infection.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Chicken, Dog (Canine), Horse (Equine), Human, Mouse, Pig (Swine), Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TNF-alpha.
- Isotype: Rabbit Ig
- Gene: P01375
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)