Product & ReviewsAntibodies

TNF-alpha Antibody

Product Details

Cat. No.
251900
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Abbiotec

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Description

Tumor necrosis factor alpha (TNF-alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces cell death of certain tumor cell lines. It is a potent pyrogen causing fever by direct action or by stimulation of IL-1 secretion, and therefore found in cachexia accompanying diverse cancers and infections. Genetic variations in TNF are associated with susceptibility to psoriatic arthritis and to HBV infection.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Cat (Feline), Dog (Canine), Horse (Equine), Human, Mouse, Pig (Swine), Rat, Sheep (Ovine)
  • Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human TNF-alpha.
  • Isotype: Rabbit Ig
  • Gene: P01375

Handling

  • Quantity: 0.1 mg
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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