Product & ReviewsAntibodies
TNF-alpha (KT61) Antibody
Product Details
- Cat. No.
- 254525
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Tumor necrosis factor alpha (TNF-alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces cell death of certain tumor cell lines. It is a potent pyrogen causing fever by direct action or by stimulation of IL-1 secretion, and therefore found in cachexia accompanying diverse cancers and infections. Genetic variations in TNF are associated with susceptibility to psoriatic arthritis and to HBV infection. This antibody recognizes human TNF-alpha in ELISA.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Recombinant human TNF-alpha protein
- Clone: KT61
- Isotype: Mouse IgG1
- Gene: P01375
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)