TORC2 rabbit antibody (pAb), sample
Product Details
- Cat. No.
- 39780
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
TORC2 (Transducer of regulated cAMP response element-binding protein 2) / CRTC2 (CREB-regulated transcription coactivator 2) is a coactivator of transcription through the CREB1 signaling pathway, independent of CREB1 phosphorylation at serine 133. Involved in metabolic signaling pathways, t is responsive to glucagon signaling and regulates gluconeogenesis. It is a potent activator of mitochondrial biogenesis in muscle cells. It is inactivated by phosphorylation at serine 171 (in response to both insulin signaling and the activation of AMPK), which facilitates recognition by 14-3-3 protein and subsequent translocation to the cytoplasm.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse
- Isotype: Serum
Handling
- Quantity: 10 ul
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Western Blotting (WB)