TriMethyl-Histone H3-K27 Rabbit pAb
Product Details
- Cat. No.
- A2363
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - TriMethyl-Histone H3-K27 antibody (A2363)
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Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
Handling
- Specificity: 5
Applications
Performs well and gives specific staining.
Immunohistochemistry, western blot
The antibody performs really well. Perfomed immunostaining with it and the staining was specific. We observed nuclear staining along with some cytoplasmic staining. Works perfectly with the dilution recommend by the manufacturer and the recommended antigen retrieval buffer.
Review Date: 17 Jun 2021 | ABclonal Technology
