Product & ReviewsAntibodies

Tryptophan Hydroxylase (Ser19) Antibody

Product Details

Cat. No.
252588
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Abbiotec

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Description

Tryptophan 5-hydroxylase 1 (TPH) catalyzes the following reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin. TPH belongs to the biopterin-dependent aromatic amino acid hydroxylase family. The activity of TPH is enhanced by phosphorylation by cAMP-dependent protein kinase (PKA) and Ca2+/calmodulin kinase II (CaM K II). CaM K II phosphorylates Ser19 which lies within the regulatory domain of TPH2.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Bovine, Mouse, Rat, Zebrafish
  • Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser19 of rat tryptophan hydroxylase.
  • Isotype: Rabbit Ig
  • Modifications: Phosphospecific Antibody
  • Gene: Q8CGU9

Handling

  • Quantity: 0.1 ml
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Western Blotting (WB)
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