Product & ReviewsAntibodies
TSHR Antibody
Product Details
- Cat. No.
- 250898
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Thyroid-stimulating hormone receptor (TSHR) is a glycoprotein secreted by the thyroid gland, and has a direct role in the thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Defects in TSHR are the cause of subclinical hypothyroidism, hyperthyroidism, thyrotropin resistance, thyroid neoplasms, Graves disease, and non-autoimmune hyperthyroidism. This antibody is mainly used for pituitary tumor classification study.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Chicken, Dog (Canine), Horse (Equine), Human, Mouse, Pig (Swine), Rat, Sheep (Ovine)
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human TSHR.
- Isotype: Rabbit Ig
- Gene: P16473
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)