Product & ReviewsAntibodies
TTF-1 Antibody
Product Details
- Cat. No.
- 251322
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Thyroid transcription factor 1 (TTF-1) is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. TTF-1 is crucial in the maintenance of the thyroid differentiation phenotype. TTF-1 plays a role in lung development and surfactant homeostasis. Defects in TTF-1 are the cause of benign hereditary chorea (BHC), a movement disorder. Defects in TTF-1 are also the cause of choreoathetosis, hypothyroidism, and neonatal respiratory distress.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human TTF-1.
- Isotype: Rabbit Ig
- Gene: P43699
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)