Tubulin-alpha Antibody
Product Details
- Cat. No.
- 250903
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Tubulin is a major cytoskeleton protein that has five distinct forms designated alpha, beta, gamma, delta and epsilon tubulin. The alpha and beta tubulins form a heterodimer that polymerize into the cylindrical microtubule fibers. Both alpha and beta tubulins bind to GTP but only beta hydrolyses GTP to GDP, leading to tubulin polymerization and microtubule formation. The alpha tubulin form can be modified by addition of a C-terminal tyrosine residue that modulates the polymerization rate. The gamma tubulin is localized in the centrosomes, which compose the core of the microtubule organizing center for microtubule fiber formation.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Alpha Tubulin.
- Isotype: Rabbit Ig
- Gene: P68363
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)