Product & ReviewsAntibodies
TUG (4A11) (Mouse) Antibody
Product Details
- Cat. No.
- 252636
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
TUG (Tether containing UBX domain for GLUT4) protein contains a UBX domain for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes and is not mobilized to the plasma membrane by insulin.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Mouse
- Antigen: Purified recombinant fragment of TUG expressed in E. coli.
- Clone: 4A11A6G11
- Isotype: Mouse IgG1
- Gene: Q9BZE9
Handling
- Quantity: 0.1 mg
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Western Blotting (WB)