TXNRD1 Rabbit mAb
Product Details
- Cat. No.
- A4725
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rabbit
Western blot - TXNRD1 Rabbit mAb (A4725)
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Description
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq, Jul 2008]
Biological Information
- Clonality: Monoclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
