Product & ReviewsAntibodies
Tyrosinase Antibody
Product Details
- Cat. No.
- 251315
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Tyrosinase is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Tyrosinase catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and 5,6-dihydroxyindole to indole-5,6 quinone. Defects in TYR are the cause of albinism oculocutaneous type 1A (OCA1A), also known as tyrosinase negative oculocutaneous albinism. OCA1A an autosomal recessive disorder in which the biosynthesis of melanin pigment is absent in skin, hair, and eyes.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human tyrosinase.
- Isotype: Rabbit Ig
- Gene: P14679
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)