Product & ReviewsAntibodies
Tyrosine 3-hydroxylase Antibody
Product Details
- Cat. No.
- 251807
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Tyrosine 3-hydroxylase (TH) plays a role in the physiology of adrenergic neurons, catalyzing the following reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4a-hydroxytetrahydrobiopterin. Defects in TH are the cause of dystonia DOPA-responsive autosomal recessive (ARDRD) also known as autosomal recessive Segawa syndrome. ARDRD is a form of DOPA-responsive dystonia presenting in infancy or early childhood. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Rabbit (Lapine), Rat
- Antigen: Rat tyrosine 3-hydroxylase.
- Clone: TH-100
- Isotype: Mouse IgG1
- Gene: P04177
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)