Product & ReviewsAntibodies
UNC13D Rabbit pAb
Product Details
- Cat. No.
- A13141
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - UNC13D antibody (A13141)
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Description
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse
