β2-microglobulin-UNLB, B1G6, 0.2 mg, RUO
Product Details
- Cat. No.
- IM0114
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The β2-microglobulin is the non-polymorphic non-covalently bound light chain (12 kDa) of the class I major histocompatibility complex (MHC-I) constitutively expressed on the surface of almost all nucleated cell. β2-microglobulin structure, stabilized by a disulfide bound, is similar to an immunoglobulin like domain. β2-microglobulin is required in the endoplasmic reticulum (ER) to associate with the MHC class I heavy molecule to form with other proteins (calreticulin, tapasin, etc.) the loading complex that exits the ER and is transported to the cell surface. After peptide presentation, β2-microglobulin is actively released into circulation.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: β2-microglobulin
- Clone: B1G6
- Conjugate: Purified
- Isotype: IgG2a
Handling
- Quantity: 0.2 mg
Applications
- Flow Cytometry (FC)