VEGFR2 antibody
Product Details
- Cat. No.
- orb11557
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Immunohistochemical staining of rat liver vessel tissue using anti-VEGFR2 (dilution of primary antibody - 1:200)
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Description
In recent decades; a variety of signaling molecules; such as VEGF-VEGFRs; ephrin-Eph receptors; angiopoietin-Tie; and the Delta-Notch system; have been identified as playing important roles in angiogenesis. Among these; vascular endothelial growth factors (VEGFs) and receptors (VEGFRs) regulate both vasculogenesis; the development of blood vessels from precursor cells during early embryogenesis; and angiogenesis; the formation of blood vessels from pre-existing vessels at a later stage3. VEGFR-1 and VEGFR-2 play major roles in physiological as well as pathological angiogenesis; including tumor angiogenesis.VEGFR-2; the major signal transducer for angiogenesis; preferentially utilizes the PLC gamma-PKC-MAPK pathway for signaling.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Dog (Canine), Human, Mouse, Pig (Swine), Rat
- Clone: NULL
- Conjugate: Unconjugated
- Isotype: IgG
- Gene: 3791
Handling
- Quantity: 100 ?g
- Storage: Store at 4°C for up to two weeks. For long term storage; aliquot and store at -20°C; avoid freeze/thaw cycles.
- Buffer: 10 mM PBS; 0.02% sodium azide
Applications
- ELISA (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
- Western Blotting (WB)
