Product & ReviewsAntibodies
WDR5 (7B11) Antibody
Product Details
- Cat. No.
- 253033
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
WDR5 (WD repeat-containing protein 5) belongs to the family of WD-40 repeat protein. It is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of human WDR5 expressed in E. coli.
- Clone: 7B11
- Isotype: Mouse IgG2b
- Gene: P61964
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Western Blotting (WB)