Product & ReviewsAntibodies

WRN mouse antibody (mAb) (Clone 195C), sample

Product Details

Cat. No.
61170
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Active Motif

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Description

WRN protein is a RECQ helicase that contains 3′ to 5′ helicase activity and DNA-dependent ATPase activity. WRN takes part in many processes, including DNA replication, recombination, repair, and telomere maintenance. Mutations in the gene encoding WRN cause an autosomal recessive segmental progeria called Werner syndrome (WS). WS patients prematurely develop atrophic skin, thin gray hair, osteoporosis, type II diabetes, cataracts, arteriosclerosis and cancer.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Clone: 195C
  • Isotype: IgG1

Handling

  • Quantity: 10 ug
  • Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Applications

  • Immunocytochemistry (ICC)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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