Product & ReviewsAntibodies
XRCC1 Rabbit mAb
Product Details
- Cat. No.
- A4135
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rabbit
Western blot - XRCC1 Rabbit mAb (A4135)
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Description
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Biological Information
- Clonality: Monoclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
