Product & ReviewsAntibodies
YAP1 Antibody
Product Details
- Cat. No.
- 254544
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
YAP (Yes-associated protein) is a transcription coactivator in the Hippo tumor suppressor pathway and controls cell growth, tissue homeostasis and in organ size. YAP is inhibited by the kinase Lats, which phosphorylates YAP to induce its cytoplasmic localization and proteosomal degradation. YAP induces gene expression by binding to the TEAD family transcription factors. Dysregulation of the Hippo-YAP pathway is frequently observed in human cancers.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser94 of human YAP1.
- Isotype: Rabbit Ig
- Gene: P46937
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)