Product & ReviewsAntibodies
Z-DEVD-FMK(CASPASE3/CPP32 INHIBITOR W-3) Antibody
Product Details
- Cat. No.
- 251610
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Caspases play significant roles in both inflammation and apoptosis. Caspases exhibit catalytic and substrate recognition motifs that have been highly conserved. These characteristic amino acid sequences allow caspases to interact with both positive and negative regulators of their activity. Thesubstrate preferences or specificities of individual caspases have been exploited for the development of peptides that successfully compete for caspase binding. DEVD-FMK is a potent inhibitor of caspase-3.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide containing the sequence DEVDFMK.
- Isotype: Rabbit Ig
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)