Ambient ionization mass spectrometry in space and time: From high throughput analysis to molecular imaging

Ambient ionization mass spectrometry has enabled a broad range of applications for mass spectrometry, thanks to the lack of need for sample preparation and the robustness of the methods. While rapid evaporative ionization mass spectrometry (REIMS) originally emerged as a method for analyzing tissues in a surgical environment, the technique quickly found applications outside of the surgical space. One of the most promising applications of REIMS is the analysis of cultured cells ranging from bacteria through fungi to mammalian cell lines. These applications have already led to the development of new microbiological identification methods and the discovery of new cancer subtypes. In this SelectScience webinar, Professor Zoltan Takats, of Imperial College London, will discuss the utility of the REIMS in the pharmaceutical or food industry as well as synthetic biology.

Mass spectrometric imaging has gradually become one of the key approaches in molecular histology. Desorption electrospray ionization (DESI) MS is one of the most popular approaches, which has benefitted from significant instrumental developments in course of the last couple of years. During the webinar, Professor Takats will also discuss the analytical performance of DESI in the context of other desorption ionization methods and review certain application areas including cancer research, drug analysis and imaging of formalin-fixed paraffin-embedded samples. A brief description of the data analysis workflows associated with these individual applications will also be covered.

Watch this webinar to learn:

• Ambient ionization mass spectrometry techniques and applications for biomedical research
• Advantages, benefits, and opportunities of ambient ionization coupled mass spectrometry imaging/molecular profiling
• Applications of REIMS (rapid evaporative ionization mass spectrometry) and benefits of DESI (desorption electrospray ionization) in mass spectrometry imaging
• The current state of ambient ionization in biomedical research and future potentials

Who should attend?

Researchers interested in:

• Mass spectrometry imaging and its applications
• Visualization of markers of disease on tissues
• Measuring the spatial distribution of a molecular species on a surface
• Adding molecular information to complement other imaging techniques
• The benefits of DESI and ambient ionization for mass spectrometry imaging.

The live webinar takes place on Thursday, October 22 at:

• 13:00 BST
• 08:00 EDT
• 05:00 PDT
• 14:00 CEST

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