BioFocus DPI Launches Compound Library Targeting Protein-Protein Interactions Plus Three New Kinase Libraries

BioFocus DPI today announced the launch of four new biologically targeted libraries. These new libraries contain novel, drug-like compounds that specifically target kinases and - for the first time - protein-protein interactions.

BioFocus DPI’s new Helix Mimetic library (HM01) is based on a novel structural motif that interacts with protein helices. This library is designed specifically to inhibit protein-protein interactions, but also targets other helical recognition motifs such as the pore region of ion channels.

BioFocus DPI’s three new SoftFocus® kinase libraries (SFK58, SFK59 and SFK60) target either the hinge region or novel binding modes. The SFK collection has been independently determined to have the greatest population of kinase-like molecules available for screening.

“Ten years after the launch of our first SoftFocus® kinase library, we are proud to launch our 100th focused library, HM01,” said Chris Newton, SVP BioFocus DPI. “This protein-protein interaction library is a reflection of our constantly evolving approach to library design, thereby providing clients with cutting-edge tools to accelerate drug discovery”.