Do you want Resolution without the need for ultra high pressure?
30 May 2007Fortis Technologies has produced an application note discussing small particle use in chromatography. Up till now everybody has seen the apparent gains that can be obtained by ultra high pressure chromatography, but do these theoretical gains actually translate into reality.
In this application paper we outline how the gains in resolution from sub 2µm particles fall significantly short of their theoretical potential. Whilst the high pressures require capital outlay the payback in terms of resolution for high-speed analysis is not automatically there. We show how well packed 3µm particles with narrow peak widths provide quality analysis in terms of resolution utilising standard HPLC systems.
You can also talk to us at ASMS in Indianapolis or HPLC in Ghent, Belgium about this study at our poster sessions.