Fast Membrane Filtration of High Particulate and Viscous Solutions

Millipore Corporation, a Life Science leader providing technologies, tools and services for bioscience research and biopharmaceutical manufacturing, today announced the expansion of its Millex^® HPF line of syringe filters, which improve throughput of high particulate and viscous solutions. Notably, Millex HPF filters are now available with a new hydrophilic Teflon^® membrane, which exhibits the broadest chemical compatibility and lowest extractability of any membrane. When used to filter samples and liquid buffers, the new Millex filters improve the quality and consistency of results, sample throughput, and the longevity of expensive analytical equipment.

The Millex HPF filter incorporates multiple media in its design: a graduated glass fiber prefilter and a membrane filter. This multi-layer filter is resistant to clogging by viscous and high particulate solutions, yet provides quantitative retention of fine particulates. Hydrophilic Teflon and nylon Millex HPF filters are now available with 0.2 µm and 0.45 µm pore sizes, meeting the needs of researchers filtering samples and mobile phases for Ultra High Pressure Liquid Chromatography (UHPLC), a very sensitive and increasingly popular separation technique.

Given their low analyte binding and low extractable characteristics, Millex HPF filters are ideal for a number of applications, including drug dissolution testing, wine analysis, and sample preparation for chromatography. The new Millex filters are specifically engineered for automatic filter-changing workstations, commonly used in high throughput sample preparation. The domed filter housing ensures reliable filter delivery, minimizing workstation downtime.