Gene Expression Analysis: A Review

This whitepaper from Plexpress provides a comprehensive review of the major methods available for gene expression analysis including microarrays, RNA sequencing, qPCR and transcript analysis and affinity capture (TRAC). The technical, time and cost implications of each method are compared. The applications of the TRAC platform in ADME-Tox, yeast culture optimization and cancer, metabolic diseases and biomarker research are described. Choice of gene expression analysis technologies are dependent on specific study needs and, with the many genome-wide and targeted options available, deciding on the best approach can be challenging. The whitepaper aims to simplify the reader’s choice of gene expression analysis by providing detailed information on each method’s applications, strengths and weaknesses.