Genedata Screener with New SPR, DMPK, HT-Flow and HT-Electrophysiology Support Showcases at SLAS2016

The software platform supports advanced screening instrumentation; extracts rich biological information from modern screening assays; harmonizes data analytics; and enables easy data access across entire research organizations.

Genedata, a leading provider of advanced software solutions for drug discovery and life science research, has announced that at SLAS2016 it will showcase how Genedata Screener 13 supports the latest screening technologies and applications. Genedata Screener extracts data from Surface Plasmon Resonance and Thermal Shift experiments, High-throughput Flow Cytometry, Automated Patch Clamp, and High Content Screening Assays and generates high-quality information on compound pharmacology. The software makes a variety of modern technologies applicable for a wide range of scientists and enables them to systematically share their data and results across research organizations. In addition to standard screening and hit-to-lead workflows, Screener supports Combination Profiling, Target Validation, DMPK, and Compound Combination Screening. These capabilities will be detailed in a series of SLAS2016 presentations and tutorials as well as at the Genedata SLAS Booth #642 (San Diego Convention Center January 23-27).

Used by More than 50% of World's Top 25 Pharmas with a successful 15-year track record of providing industrial-level screening data analysis, today Genedata Screener is used by the majority of leading global pharmaceutical companies, as well as many CROs and academic research institutions. “We believe that Genedata Screener is the gold standard for screening data analysis” said Dr. Steve Rees, vice president of Screening Sciences and Sample Management at AstraZeneca.

The Genedata Screener platform is continuously evolving to support the latest generation of complex technologies and applications. This evolution is rooted in deep customer collaborations that drive innovative developments, which are regularly made available to the scientific community in new software releases.

Genedata Screener 13 will be shown at SLAS2016 featuring:

* High-throughput Flow Cytometry (HT-Flow) for analysis of complete campaigns in a single session with interactive QC on cell- and well-level data.

* Biophysical Screening using a range of technologies such as Impedance, Surface Plasmon Resonance (SPR), and Thermal Shift Analysis (TSA).

* High-throughput Electrophysiology - Automated Patch Clamp (APC) experiments that integrate raw data, analysis, and storage/reporting into one optimized workflow.

* Drug Metabolism and Pharmacokinetics (DMPK) for increased analysis efficiency and result comparability for MS-based in-vitro clearance, lipophilicity, and solubility assays.

* Easy integration for complex instrumentation with the Genedata Ready-to-Run program, which is pioneering out-of-the-box integration with selected instrument platforms. Increasingly, instrument vendors are joining Read-to-Run to ensure their customers have a smooth instrument integration workflow. More information available here.

Built for Collaboration

The trend towards collaborative research models is on the rise with pharmaceutical companies outsourcing projects to CROs and partnering with each other and academic screening centers. Genedata Screener provides the common platform for such collaborations as it provides standard semantics for data analysis. It also enables data and result transparency among colleagues - but more importantly – it provides a full understanding of data and results including all relevant quality indicators. Such insights are requisite for fact-based decision making as result sharing is meaningless without ensuring result integrity and traceability back to the instrument level.

“We believe Genedata Screener has become the industry-leading data analysis platform because it consistently adapts to support new screening technologies and enables close collaborations and result sharing within the scientific community,” noted Dr. Othmar Pfannes, CEO of Genedata. “Screener is emblematic of the entire Genedata solution portfolio, which continuously pushes the envelope in support of the latest technologies as well as advancing the pace of automated data analysis.”