Innovating Correlative Light Electron Microscopy and Volume Imaging Technology Through Discussion at EMBL 3D

SelectScience® spoke to Dr Yannick Schwab, Team Leader and Head of Electron Microscopy Core Facility at the European Molecular Biology Laboratory (EMBL), about a recent conference organized in conjunction with ZEISS Microscopy

European Molecular Biology Laboratory (EMBL) Founded in 1974, EMBL is Europe’s flagship laboratory for the life sciences – an intergovernmental organization with more than 80 independent research groups covering the spectrum of molecular biology.

EMBL is an intergovernmental organization specializing in basic research in the life sciences, offering important services to scientists from its member states and developing new technologies and methods. In March 2016, at its main site in Heidelberg, Germany, EMBL hosted a workshop on 3D Light and 3D Electron Microscopy (EMBL 3D), in conjunction with ZEISS Microscopy. We spoke to one of the organizers, Dr Yannick Schwab, about the exciting innovation discussed at the event.

“Our goal at this conference was to bring together as many leaders in the field as we could”, Dr Schwab explained. The conference enabled them “to share the latest developments in the field and also to take new people in the field and enable them to catch up”. “Even though this is a focused conference, we have many, many things to share, many different techniques and approaches, fostering new ideas.”

“Correlative microscopy is not a new technique, but it bridges two worlds - the study of functional dynamic events in biological systems, from cultured cells to organisms, together with high resolution anatomical data”, revealed Dr Schwab. “We are now witnessing an interesting time where correlative microscopy is becoming a measurement tool to answer questions about more and more complex biological systems”.

EMBL3D

EMBL3D offered presentations on “correlative light electron microscopy, volume imaging using mostly scanning electron microscopy and a bit of transmission electron microscopy”. “Volume imaging and electron microscopy are very interesting because, now, we can address cells, cell populations and tissues at high resolution and for large areas of volumes of cells”, Dr Schwab explained. “Together with correlative microscopy, this is getting very powerful.”

The great thing about the electron microscopy community, revealed Dr Schwab is “people are willing to share a lot. For example, during this conference, a few speakers were even sharing data that was not published”. He believes this sharing mentality is “fruitful for the whole community, and is moving the whole field forward”. Although this conference was “very technology oriented”, scientists are already seeing that “this advanced technology is enabling science” in a range of applications. “Answering biological questions with correlative volume microscopy is a recent advance, and that’s really exciting.”

Find out more about the other speakers and presentations from EMBL 3D, or learn more about the applications of Correlative Microscopy.

Watch our interview with Dr Schwab here.