Integrated DNA Technologies and Element Biosciences, Inc. announce enhanced partnership

Life sciences companies Integrated DNA Technologies (IDT™) and Element Biosciences, Inc. have bolstered their partnership with products to enable more efficient and streamlined next-generation sequencing (NGS) workflows for users of the AVITI™ System, an innovative sequencing and multi-omics platform based on Element’s novel avidity base chemistry.

A suite of high-quality adapters, universal blockers and library amplification primer mixes designed exclusively for the AVITI System has been developed. These products can support a wide range of applications, including DNA, RNA, and methylation sequencing workflows, as well as IDT’s hybridization capture chemistry. They are also intended to minimize sequence errors from PCR or sequencing that might impact demultiplexing.

To support Element’s AVITI System with native library construction and hybridization capture enrichment, IDT is offering these stocked AVITI products:

• xGen Stubby Adapter-UDI Primers for Element – stubby adapter and unique dual-index primer pairs for TA-ligation library preparation workflows where indexing by PCR is preferred. Available as single-use plates containing either 16 or 96 indexes, and a separate tube of stubby adapters with a matching number of reactions.

• xGen Universal Blocking Oligos for Element – proprietary blockers designed specifically for Element Biosciences libraries for use in the hybridization capture workflow to reduce non-specific adapter interaction during probe hybridization and increase on-target capture performance. Available in 16 or 96 reaction sizes.

• xGen Library Amplification Primer Mix for Element – premixed PCR primers, available in 16 or 96 reaction sizes, to increase yield for sequencing libraries post-hybridization capture.

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