MACHEREY-NAGEL, the manufacturer of NUCLEOSIL^®, introduces the new NUCLEODUR^® application booklet

The 53-page publication introduces all available NUCLEODUR^® phases with various applications including HPLC columns, filled with the new high performance 1.8µm particles and a unique new C18 phase with outstanding shape selectivity (NUCLEODUR^® C18 ISIS) for various separation problems.

Also introduced are NUCLEODUR^® phases like the hydrophilic (polar) endcapped NUCLEODUR^® C18 Pyramid phase and the the fully endcapped NUCLEODUR^® 100-5 CN-RP HPLC column for reversed phase applications, which provide a broader scope in selectivity as C8 and C18 phases. The NUCLEODUR^® C18 Pyramid can be used in mobile phase systems of up to 100% water and is particularly suited for the separation of polar compounds.

Moreover NUCLEODUR^® C8 / C18 Gravity columns are presented. The special surface bonding technology and the low concentration of metal impurities make it possible to run the column at an extended pH working range from 1 – 11.

The dual mode NUCLEODUR^® Sphinx RP phase is characterized by exceptional selectivity features generated by a well-balanced ratio of covalently bonded octadecyl- and phenyl groups. The combination of classical hydrophobic with π-π interactions (aromatic ring system) expands the scope of selectivity in comparison with conventional reversed phase packings. NUCLEODUR^® Sphinx RP is particularly suited for the separation of molecules containing aromatic and multiple bonds. Different from standard phenyl phases NUCLEODUR^® Sphinx RP is not susceptible to hydrolysis and is also suggested for LC/MS applications.

Further information can be found on the article webpage.