New Gas Analyzer for Monitoring Cell Growth Processes

Over the next few days, the German company BlueSens will be presenting the new BlueInOne Cell gas analyzer. The new analyzer for carbon dioxide and oxygen has been specially designed for monitoring cell growth processes in biotechnology.

The device can be installed directly in the exhaust flow of the bioprocess and measures the concentration of CO2 and O2 there in real-time. The BlueInOne Cell automatically compensates any fluctuations of pressure and humidity in the system. The readings are therefore extremely reliable even under fluctuating measuring conditions. “The new BlueInOne Cell is a cost-effective, extremely uncomplicated, reliable and accurate in situ gas analysis for cell growth processes,” explains Dr. Holger Müller, one of the managing directors of BlueSens.

The new oxygen sensor element in the analyzer is now able to record all oxygen concentrations reliably from 0 % to 100 % volume. Anaerobic processes can also be monitored with the new analyzer. “In the development stage, we particularly focused on long-term stability and high resolution,” emphasizes Dr. Müller. The BlueInOne Cell has a correspondingly extremely high resolution of 50 ppm and could be used as a replacement for cost-intensive mass spectrometers which are frequently used. The modern BlueInOne Cell incorporates all measuring components in one compact and durable stainless steel housing and is very easy to install directly on the gas pipe. Using standard interfaces, such as Modbus or USB, it can be connected to any process control system or PC. With automatic, continuous monitoring and documentation of the growth process, there is no need for sampling. The operating status of the BlueInOne Cell can be read anytime by checking the illuminated buttons.

The BlueInOne Cell is the second analyzer in the BlueInOne combined sensor series. The BlueInOne Ferm has already been available for monitoring fermentation processes since last October. Both sensors will be used in the worldwide “BlueCompetition” scientific contest between biotechnological institutes at universities. As well as the Cell and Ferm, more combined analyzers are planned for other gas components as part of the BlueInOne series in future.