New Resin for the Capture and Large-Scale Purification of Monoclonal Antibodies

Tosoh Bioscience LLC introduces Toyopearl AF-rProtein A-650F resin for the capture and large-scale purification of monoclonal antibodies. This resin contains an alkaline resistant recombinant Protein A variant bound to the resin by multipoint attachment.

The Toyopearl AF-rProtein A-650F resin is synthesized using a novel recombinant Protein A ligand bound to the 45 micron, 1,000Å pore size base bead, using multipoint attachment. The ligand is non-animal derived. The new resin can tolerate CIP in both 0.1mol/L and 0.5mol/L NaOH.