PurePep EasyClean Auto Kit for automated parallel peptide purification
Gyros Protein Technologies introduces new automated kit to overcome major bottleneck in peptide production
27 Jul 2023
Gyros Protein Technologies AB, a provider of peptide synthesizers and reagents, and automated nanoliter-scale immunoassays, has announced the launch of its PurePep® EasyClean (PEC) Auto Kit for the automated parallel purification of peptides, accelerating downstream processes for research, development, and production of simple to complex peptide drugs and therapies.
Based on Gyros Protein Technologies’ orthogonal PurePep EasyClean technology, the PEC Auto Kit utilizes a simple catch-and-release methodology for purification of chemically synthesized peptides. The new Auto Kit allows users of the PurePep Chorus and Symphony® X synthesizer to perform peptide synthesis and purification on a single instrument, further increasing process efficiency.
Conventional chromatography, including reversed-phase liquid chromatography (RP-HPLC) is a major bottleneck in peptide production, both in academia and industry, due to its limited capacity in higher throughput purifications, and the significant volumes of toxic solvents required. In addition, operation of RP-HPLC is labour intensive and requires specialist skills. Gyros Protein Technologies’ PEC Auto Kit has been designed to require up to 90% less hands-on time per peptide (6 minutes vs ~ 1 hour) and 90% less solvent consumption, facilitating parallel purification of 6 or more purified peptides in under 6 hours.