Revolutionary Technologies Create a New Generation of HPLC Column

26 Apr 2006

The new Teknokroma Mediterranea sea18 HPLC column from Qmx Laboratories provides an unsurpassed performance in efficiency, inertness, pH robustness, reliability and reproducibility.

There is a strong consensus that silica is the best packing material for HPLC columns. However, critical to its performance is the need to control purity and porosity whilst minimising the presence of active sites.

Drawing on over 25 years of experience our researchers have developed novel purification, bonding and packing technologies to create a C18 phase of extraordinary properties.

The Teknokroma Mediterranea sea18 column uses perfectly spherical, rigid and inert silica particles with an ultra low metal content. Surface Enhanced Accessibility (SEA), a proprietary purification process, controls pore distribution, ensures structural strength and chemical inertness, and delivers a high load capacity to achieve greater separation efficiency.

Multifunctional Endcapping Deactivation (MED) chemistry maximises surface bonding ensuring symmetrical peaks from even the most acidic or basic pharmaceuticals and their metabolites. A resulting protective shield provides resistance to extreme pH values over the range 1 to 12.

Low column bleed and fast, consistent separations make the Ultra-rapid column configurations ideal for high-sensitivity, reverse phase LC-MS applications. Ultrafit, a new column design, enables fast, easy maintenance whilst allowing additional frits or a pre-column to be included with the utmost simplicity and economy without loss of separation efficiency.

Rigorously developed purification technologies and bonding chemistries ensure that the Teknokroma Mediterranea sea18 columns deliver outstanding performance, reproducibility and long life.

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