Thermo Fisher Scientific Introduces a Tailor-Made Peptide Library for the Development of SRM Assays

Thermo Fisher Scientific Inc., the world leader in serving science, today introduced Thermo Scientific PEPotec SRM, a custom peptide library that is designed for medium to high-throughput development of single-reaction monitoring (SRM) assays. The library offers greater convenience and flexibility while accelerating mass spectrometry quantitative workflows by reducing setup time.

The PEPotec™ SRM consists of fully synthetic crude peptides, with a length of six to 25 amino acids. Peptides are supplied in quantities of >0.1 milligram, with the minimum order quantity of 24 peptides. Typically, libraries are manufactured in a minimum of seven days. Peptides are available in a 96-well tube array format.

In addition, researchers requiring further customization can order tailor-made libraries through the PEPotec SRM optional services. Custom options include choice of C-terminal amino acids, longer peptides, phospho groups, carbamidomethylation or labeling with isotopes for high-throughput SRM assays, also known as multiple-reaction monitoring (MRM) assays.

The PEPotec SRM offering was developed as a result of Thermo Fisher’s involvement in the SRM Atlas project at the Institute for Systems Biology in Seattle, which seeks to map the entire human proteome with the help of hundreds of thousands of Thermo Scientific HeavyPeptides and custom peptides.

“With PEPotec SRM, the broader research community now has access to the unique expertise, quality, manufacturing processes and pricing that we have developed for the SRM ATLAS project,” said Joel Louette, commercial director for Thermo Scientific custom biopolymers. “We are confident that these unique peptide libraries will enable our customers to advance science.”