Thermo Fisher Scientific Introduces New Reagents for Nanoparticle Development

Thermo Fisher Scientific has introduced a new group of Thermo Scientific PEGylation Reagents specifically for use in the development of gold or silver nanoparticles, self-assembled monolayers, quantum dots and magnetic particles. The high purity polyethylene glycol (PEG) compounds of defined chain length help produce precise surface characteristics and minimize non-specific interactions, which are important for these applications.

Two varieties are available: Methyl- and Carboxy-thiol PEGylation Reagents and Methyl- and Carboxy-lipoamide PEGylation Reagents. The thiols form dative bonds when bound to gold surfaces. Monodentate thiols, such as Methyl- and Carboxy-thiol PEGylation Reagents, can be easily removed by compounds such as DTT. Bidentate thiols, such as Methyl- and Carboxy-lipoamide PEGylation Reagents, provide an added level of stability to the nanostructure and are much more resistant to removal from the metal surface by DTT or similar reagents.