Would you like new and practical LC-MS solutions for FAST and ACCURATE quantitation and qualification of trace level impurities and polar metabolites?

Phenomenex’s FAST Solutions and new HILIC phase offer particle and selectivity benefits that significantly decrease development time at all stages of the drug development process. With selective, robust, stable, and reproducible technologies that are practical for every lab, Phenomenex makes mass sensitive quantitation and qualification of polar compounds straightforward. We will even supply you with a HILIC Method Development 'Roadmap to Success'! Join us on Wednesday, 20 June, 14.00 at Easy Implementation: New Approaches in Fast LC & HILIC Chromatography.

Be amongst the first to implement these proven strategies in your lab!

New Approaches in Fast LC & HILIC Chromatography.

Do not miss the workshop Easy Implementation: New Approaches in Fast LC & HILIC Chromatography, on Wednesday, 20 June, 14.00. In this workshop, we will present successful strategies that labs everywhere will be able to implement to significantly reduce method development time at all stages of the drug development pipeline. 2.5µm HST columns and a new HILIC phase will take advantage of the impact of selectivity on resolution in high speed separations.

The discussion will explode the myth that higher plate counts alone lead to better resolution and faster runs. The Resolution equation, the Van Deemter theory, the Selectivity Equation and the many variables that are involved in assay performance can be applied and manipulated to create a more elegant, fast solution. Focusing on efficiency alone will be shown to be a brute force way to improve chromatographic resolution.
We will discuss:

• Increasing speed with 2.5 µm materials
• Effect of selectivity on resolution in high speed separations
• Influence of particle surface area on column loading capacity
• Effect of system volumes on column performance in high speed separations

An additional discussion will focus on the broad applicability and need for a HILIC Roadmap to Success. Historically, low-level polar metabolites and impurities have slowed development progress and lowered mass spectrometric sensitivity. Phenomenex’s new Luna HILIC column and our comprehensive HILIC method development process offer a true, ‘Roadmap to Success’ for separation, quantitation and qualification of complex mixtures of polar compounds.