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3-Methyladenine
PI3K/AKT pathway inhibitor
3-Methyladenine
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3-Methyladenine has been reported to inhibit autophagy (Seglen & Gordon) by blocking autophagosome formation via the persistent inhibition of class I and transient inhibition of class III phosphoinositide 3-kinase (PI3K; Wu et al.).
METABOLISM
- Inhibits autophagy in isolated rat hepatocytes (Wu et al.).
