3dGRO™ Human iPSC Derived Colon Organoids
Highly characterized, cryopreserved human colon intestinal organoids derived from integration-free human induced pluripotent stem cells (iPSCs).
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3dGRO™ Human iPSC Derived Colon Organoids are derived from integration-free human iPS cells reprogrammed using Simplicon RNA technology. Epithelial intestinal organoids, often referred to as enteroids or mini-guts, maintain the physiological characteristics of the gastrointestinal system and have been a useful cell culture tool to model intestinal development and disease including colon cancer, celiac disease, inflammatory bowel diseases, and host microbiome interactions. 3dGRO™ Human iPSC Derived Colon Organoids express colon-specific markers including the posterior hindgut marker CDX2, a-carbonic anydrase II (CA-II), a-carbonic anhydrase IV (CA-IV), and goblet cell markers Mucin-2 and Mucin-5B and can be used as 3D cell models to study intestinal diseases.
