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5-Bromo-2′-deoxyuridine

Merck KGaA, Darmstadt, GermanyB5002Available: Worldwide

≥99% (HPLC)  

Merck KGaA, Darmstadt, Germany

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5-Bromo-2′-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.

5-Bromo-2′-deoxyuridine has been used:

  • as a supplement to study the effect of electroconvulsive seizures on hippocampal neurogenesis
  • as a supplement to study the loss-of-gene function in adult zebrafish heart
  • in T lymphocyte proliferation assay{133]

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