Action Potential Duration (APD) Testing on hESC-Derived Cardiomyocytes
Evaluate compounds in human stem cell-derived, ventricular-type cardiomyocytes. Effects on action potential parameters are evaluated in single human cardiomyocytes using patch-clamp recording Benefits: Human ion channels expressed in a native cardiac environment Detects AP Prolongation (QT risk) and EADs (Torsade trigger) Stable recordings at physiological temperature with minimal diffusion delays Cost-effective Ra…
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Evaluate compounds in human stem cell-derived, ventricular-type cardiomyocytes. Effects on action potential parameters are evaluated in single human cardiomyocytes using patch-clamp recording
Benefits:
- Human ion channels expressed in a native cardiac environment
- Detects AP Prolongation (QT risk) and EADs (Torsade trigger)
- Stable recordings at physiological temperature with minimal diffusion delays
- Cost-effective
- Rapid turnaround time
