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AdvanceBio Oligonucleotide Columns

Agilent TechnologiesAvailable: Worldwide

To successfully separate trityl-off, deprotected oligonucleotides, you need columns that have high resolving power and are robust enough to withstand challenging conditions.

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To successfully separate trityl-off, deprotected oligonucleotides, you need columns that have high resolving power and are robust enough to withstand challenging conditions.

If your columns don’t provide enough resolution, you can’t be sure your results are accurate. If your columns are not robust, you will have to replace them frequently, which will disrupt your workflow and increase your costs.

Agilent AdvanceBio oligonucleotide columns feature high efficiency, 2.7 μm superficially porous Poroshell particles. Using technology exclusive to Agilent, we chemically modify the particles to make them exceedingly resistant to high pH mobile phases. We also bond them with an end-capped C18 phase that delivers excellent selectivity for oligonucleotides. What’s more, we test every batch of AdvanceBio oligonucleotide media with a resolution standard to ensure consistent performance.

The family of AdvanceBio products are designed to deliver consistent, exceptional performance for the complete characterization of proteins, antibodies, conjugates, new biological entities and biopharmaceuticals.

Features:

  • High resolution oligonucleotides separations with long column lifetime on HPLC and UHPLC systems.
  • Improve reliability of results – high-resolution separations delivered by efficient Poroshell particle morphology
  • Reduce costs – long column lifetimes from robust, high-pH resistant chemically modified silica
  • Increase flexibility – compatibility with HPLC and UHPLC systems via 2.7 μm diameter particles

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