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Agilent 1260 Infinity III Prime Bio Analytical-Scale LC Purification System

The 1260 Infinity III Prime Bio Analytical-Scale LC Purification System is a versatile preparative high-/ultrahigh-perfomance liquid chromatography (HPLC/UHPLC) system for bioseparations. The system offers outstanding functionality and operational convenience for bioanalytical HPLC and entry-level quaternary bio UHPLC at pressures up to 800 bar and flow rates up to 5 mL/min.

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This biocompatible HPLC/UHPLC system is the ideal system when you need to investigate separated compounds. The 1260 Infinity II Bio-Inert Fraction Collector offers a cooling module to prevent degradation of thermally labile biomolecules.

The system consists of biocompatible material for use in biopharma (such as for critical quality attributes) and other applications using high-salt and extreme-pH conditions, ensuring biomolecule integrity and system robustness.

Features

  • Biocompatible solvent and sample flow path, ensuring integrity of biomolecules and minimizing unwanted surface interaction.
  • High-salt tolerance and a wide pH range, offering enhanced flexibility and robustness for increased instrument uptime.
  • Power range combines high pressure up to 800 bar and high analytical flow rates up to 5 mL/min, maximizing UHPLC performance.
  • System based on proven 1290 Infinity III technology for easy method transfer (also available from legacy instrumentation), reducing training effort.
  • Shallow microplate drawers take a maximum load of 6,144 samples, creating unmatched sample capacity.
  • Buffer Advisor software provides a fast and simple way to create salt and pH gradients, eliminating the tedious and error-prone method development steps of buffer preparation, buffer blending, and pH scouting.
  • Wide range of sensitive optical detection capabilities with various flow cells enablevariable wavelength, diode array, fluorescence, or LC/MS detection, enhancing adaptability.
  • Collection of up to 4 x 96 fractions in microtiter plates, or up to 216 fractions in glass tubes—with four outer diameters available, increasing flexibility.
  • Integrated and automated fraction delay sensor technology, increasing purity and recovery of collected fractions.
  • Upgradable fraction capacity based on your demand, improving lab efficiency through orthogonal analytical information that is only available from isolated compounds.

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