Agilent 1290 Infinity III Bio Analytical-Scale LC Purification System
The 1290 Infinity III Bio Analytical-Scale LC Purification System is an ultrahigh-performance liquid chromatography (UHPLC) system, configurable with a binary or quaternary pump and consisting of biocompatible material for use in biopharma (such as for critical quality attributes).
This preparative system is the most flexible and versatile solution for compound isolation using high-salt and extreme-pH conditions. The biocompatibility of this preparative UHPLC system ensures biomolecule integrity and system robustness.
This UHPLC system is ideal for purification of multimilligram quantities of materials. A variety of bio flow cells are available for sensitive UV detection. Plus, the 1260 Infinity III Bio-inert Fraction Collector offers a cooling module to prevent degradation of thermally labile biomolecules.
Features
- Biocompatible solvent and sample flow path, ensuring integrity of biomolecules and minimizing unwanted surface interaction.
- Lowest delay volume throughout the system, enabling highest chromatographic resolution and lowest dispersion.
- High-salt tolerance and a wide pH range, offering enhanced flexibility and robustness for increased instrument uptime.
- System based on proven 1290 Infinity III technology for easy method transfer (also available from legacy instrumentation), reducing training effort.
- Shallow microplate drawers take a maximum load of 6,144 samples, achieving unmatched sample capacity.
- Power range combines ultrahigh pressure up to 1300 bar and high analytical flow rates up to 5 mL/min, maximizing UHPLC performance.
- Wide range of sensitive optical detection capabilities with various flow cells, enabling variable wavelength, diode array, fluorescence, or LC/MS detection for highest adaptability.
- Collection of up to 4 x 96 fractions in microtiter plates, or up to 216 fractions in glass tubes—with four outer diameters available, increasing flexibility.
- Integrated and automated fraction delay sensor technology, increasing purity and recovery of collected fractions.
- Upgradable fraction capacity based on your demand, improving lab efficiency through orthogonal analytical information that is only available from isolated compounds