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Agilent 1290 Infinity III Bio Online Sample Manager

The 1290 Infinity III Bio Online Sample Manager combines the 1260 Infinity III Online Sample Manager and the 1290 Infinity III Bio Multisampler, offering a biocompatible flow path and a maximum pressure capability of 1300 bar for the most demanding bioprocess monitoring applications.

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Agilent Technologies

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The Online Sample Manager mediates sample diluent incompatibility in challenging bioprocess samples by supporting both flowthrough and Agilent Feed Injection methods. It automates dilutions up to 1:1000, and offers retain-sample functionality for further analysis. The system also enables direct analysis of process samples and provides automated sample preparation.

Features

  • Connects the analytical and process worlds in PAT applications via an external sampling interface for automated bioprocess monitoring
  • Provides a wide range of sampling volumes (0.1 to 100 µL) for flexible injection of process samples
  • Enables fast bioprocess monitoring of critical process parameters and quality attributes through direct injections, delivering real-time data for enhanced control and process understanding
  • Supports automated dilutions, reaction quenching, sample preparation, and archiving via retain-sample functionality
  • Offers efficient sample handling with a capacity of 432 vials (2 mL) for at-line sample analysis or online retain-sample functionality
  • Uses hybrid injection technology for seamless method transfer and effective sample dilution control, including a biocompatible flow path
  • Includes integrated sample thermostat option for handling temperature-sensitive samples (4 to 40 °C)
  • Ensures integrity of biomolecules and minimizes unwanted surface interactions through biocompatible flow path


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