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Arbidol
Blocks fusion between virus and target host cells
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Arbidol is a broad-spectrum antiviral compound that blocks membrane fusion between virus and target host cells (Leneva et al.; Teissier et al.). It is effective against numerous viruses, including influenza A, B, and C, and hepatitis B and C, with IC50 values ranging from 3 - 12.5 µg/mL (Boriskin et al.). This product is supplied as the hydrochloride salt of the molecule.
DISEASE MODELING
- Reduces viral replication and acute inflammation through modulating the expression of inflammatory cytokines such as interleukin 1β, interleukin 6, interleukin 12, and tumor necrosis factor-α (Liu et al.).