Avanti® Polar Lipids 18:1 Lyso PA
1-oleoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), powder
Biological responses to LPA: Cell Proliferation, Inhibition of differentiation (neuroblastoma cells, myoblasts), Platelet aggregation, Smooth muscle contraction, Neurotransmitter release, Stress fibre formation/cell rounding/neurite retraction, Cell-surface-fibronectin binding, Tumor cell invasion, Chemotaxis (dictyostelium amoebae), Cl--mediated membrane depolarization (fibroblasts), Inhibition of connexin 43 based cell-cell communication, Increased tight junction permeability (brain endothelial cells). Note: The bioactivity of LPA appears to require long (i.e., C16 to C18) acyl carbon chains of the type usually found associated with membrane lipids although optimum requirements for a single type of acyl carbon chain are not universal. The bioactivity decreases with shorter chain length. In serum, oleoyl and palmitoyl fatty acid containing LPA are the predominant species.
Packaging
- 5 mL Clear Glass Sealed Ampule (857130P-200mg)
- 5 mL Clear Glass Sealed Ampule (857130P-25mg)
- 60 mL Amber Wide Mouth Screw Cap Glass Bottle (857130P-1g)