Products & ReviewDrug discovery > Drug Manufacturing
Avanti® Polar Lipids Brain PI(4,5)P2
Merck KGaA, Darmstadt, Germany840046XAvailable: ,Western Europe,Asia,Eastern Europe,South Central America,Caribbean,Australia Oceania,Middle East,Africa,Other
L-a-phosphatidylinositol-4,5-bisphosphate (Brain, Porcine) (ammonium salt), chloroform:methanol:water (20:9:1)
Buy Now
Place your order directly with the manufacturer.
Although PI(4,5)P2 is a minor component of cell membranes, it plays a critical role as a substrate for a number of important signaling proteins. PI(4,5)P2 is an intermediate in the IP3/DAG pathway where it is hydrolyzed by phospholipase C to liberate the second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PI(4,5)P2 is also a substrate for PI 3-kinase where it is phosphorylated to PI(3,4,5)P3, an activator of downstream signaling components such as the protein kinase AKT.
Packaging
- 5 mL Clear Glass Sealed Ampule (840046X-10mg)
- 5 mL Clear Glass Sealed Ampule (840046X-1mg)
- 5 mL Clear Glass Sealed Ampule (840046X-25mg)
- 5 mL Clear Glass Sealed Ampule (840046X-5mg)
