BI SPR 4500
A 5-channel high throughput SPR instrument with high sensitivity and fast detection for protein studies.
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Great result! Reliable instrument
Measure the Kd
I have used BI SPR 4500 to measure the Kd binding affinity between my protein and ligands. The instrument is really easy to use. The software comes with it is user-friendly. Also, the machine helps me to produce the same result all the time I repeat the experiment. The background is low and that allows me to have a good binding response after subtracting the background. The machine has five channels so you can choose the best channel after analyzing data. Also, you can run each channel separately so you can run many ligands as you want or you can immobile different proteins in each channel and then flow your ligands to all channels. The company provides different kinds of chip sensors so you can choose the one that is suitable for your immobilized strategy. I would recommend this machine to any users.
Review Date: 2 Mar 2023 | Biosensing Instrument
The 5-channel Surface Plasmon Resonance (SPR) instrument, combined with the BI Autosampler, is the ideal solution for high throughput assay development. With the BI-DirectFlow™ technology, it provides precise sampler delivery and high-quality binding kinetic measurements.
High throughput with 5 channels and fully automated Autosampler Provides 5 channel flow modes and high sample capacity with up to two 384 well plates.
High sensitivity Delivers high-quality binding response for low immobilization and small molecule (< 100 Daltons) detection.
Precise sample delivery with BI-DirectFlow™ Technology Delivers sample with near-zero dispersion for fast kinetics and effective removal of various secondary effects.
Temperature-controlled SPR detection module covers a wide SPR angle range for measuring SPR shift in liquid phase. Precision background and reference subtraction. Temperature control for thermodynamic studies, 6 °C to 50 °C.
Innovative multi-module design Provides users with maximum flexibility to choose from various analysis modules for electrochemistry and liquid applications.
