Products & ReviewLife Sciences
Cardiogenol C
Inducer of cardiac differentiation
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Cardiogenol C is a diaminopyrimidine that induces cardiomyogenesis in mouse embryonic stem cells. Its use results in expression of GATA-4, MEF2, and Nkx2.5.
REPROGRAMMING
- Induces trans-differentiation of mouse CD34+K15+ hair bulge progenitor cells into cardiomyocyte-like cells (Yau et al.).
- Induces cardiomyogenic function in the lineage-committed progenitor cells, C2C12 skeletal myoblasts and mouse A5 cardiovascular progenitor cells (Mike et al.).
DIFFERENTIATION
- Induces the differentiation of myosin heavy chain (MHC)-positive cardiomyocytes from mouse embryonic stem cells (Wu et al.).